Articles about Eye Health and Disease 2001
Association between Cataract and Increased Mortality
Rate in Blacks
(From A Hennis, PhD et al. Lens Opacities and Mortality: The
Barbados Eye Study. Ophthalmology 2001;108:498-504.)
The Barbados Eye Study measured the prevalence and risk factors for
major causes of visual loss among 4709 Barbadian-born citizens, aged 40 to
84 years (1988-1992). Individuals were randomly chosen for the study,
which included a comprehensive eye examination, which was then repeated in
four years. In this study looking at cataract vs. cause of death, 306 of
4314 black participants had died before the four year follow-up. The type
of cataract that these individuals had were compared to cataract in the
surviving population.
Cataracts are a clouding of the natural lens of
the eye. This can lead to visual loss, symptoms of glare and halos around
lights, and changes in a glasses prescription. There are different types
of cataract when examined by an ophthalmologist. A nuclear sclerosis
cataract is a generalized haziness throughout the lens. A cortical
cataract is a sheet-like or spoke-like clouding of the front part of the
lens. A posterior subcapsular cataract is a crust-like clouding
across the back of the lens.
This study found that the type of cataract that an individual had at
the initial examination was a risk factor for death within the following
four years (before the follow-up examination):
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Those without cataract had a 3.2% mortality rate within four years.
-
Those identified as having "mixed cataracts", meaning that
the lens had a mixture of different types of cataract, had a 20.9%
mortality rate.
-
Those with the "nuclear sclerosis" type of cataract had a
8.8% mortality rate.
-
Those with the "cortical" type of cataract had a 6.0%
mortality rate.
-
Cardiovascular disease was the principal cause of death in black
participants, followed by cancer.
-
The death rate risk increased with age, peaking at 60 to 69 years.
-
Diabetes further increased the mortality risk, and those with
diabetes and the mixed type of cataract had a 2.7 fold increased risk
of death.
Overall, this study is the first to identify a relationship between type
of cataract and mortality in an African-descent population.
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