Articles about Eye Health and Disease from 2000 and earlier:
Artificial Solar Cell Retinal Implant Undergoing
Clinical Trials in Retinitis Pigmentosa Patients
Optobionics Corporation has
developed an artificial silicone retinal implant using solar cell
technology that is undergoing clinical trials in humans, starting in June
2000. After 6 years of animal research, the FDA allowed the implants to be
surgically placed beneath the retinas of 3 human volunteers to evaluate
their biocompatibility, and potentially, their functionality. Dr. Alan
Chow MD, an ophthalmologist, was interested in developing an implant that
could electrically stimulate the retina to create some level vision for
those patients with severe visual loss from retinitis pigmentosa (RP). In
RP, the photoreceptor layer of the retina degenerates, leading to
progressive visual loss. The condition often runs in families, and can
lead to severe loss of vision in both eyes. There are hundreds of millions
of photoreceptors in the retina which convert light impulses to electrical
signals. The signals are carried by nerve tissue within the retina to the
ganglion cell layer, which sends the visual signal to the brain through
the optic nerve. In retinitis pigmentosa, the ganglion cell layer remains
intact.
The artificial silicone retinal implant is 2mm in diameter, and is
one-thousandth of an inch thick. There are thousands of solar cells on the
surface of the the chip, which each generate a small electrical current in
the presence of light. This current is transmitted to retina, as the chip
is surgically placed beneath the retina.
At the Annual Meeting of the American Academy of Ophthalmology in
October, 2000, it was reported that the implanted retinal chips were
showing no signs of rejection, migration, or other complications.
Information about any vision being stimulated by the chips has not been
released at this time.
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| Retinal Implant is about 2
millimeters in diameter |
Retinal Implant shown under
the retina of the macula near the optic nerve (structure to the
right with vessels coming out from it) |
Surface of Retinal Implant
showing thousands of solar cells |
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